About Us
Our Services
Events
Publications & Presentations
NRL News
Publications
Presentations
Annual Report
Resources & Guidelines
Contact & Feedback
BloodGroup
QConnect
OASYS



Publications

 

Best Practice Laboratory Testing for Transfusion Transmissible Infections

Susan Best, Wayne Dimech, Roderick Chappel
A Textbook on Laboratory and Clinical Transfusion Medicine, Volume 2: Basics of Blood Bank Practices (Process Control).

Ed. Nabajyoti Choudhury, Ed. Zarin Bharucha.
NY: Nova Science Publishers, 2016. Print

Quality Management of Point-of-Care Testing Devices

Mark Shephard, Anne Shephard, Wayne Dimech and Susan Best
A Practical Guide to Global Point of Care Testing. Ed. Mark Shephard. Australia: CSIRO Publishing, 2016. 54-65. Print

Human T-Lymphotropic Virus type 1 infection in an Indigenous Australian population: epidemiological insights from a hospital-based cohort study

Einsiedel L, Woodman RJ, Flynn M, Wilson K, Cassar O, Gessain A
BMC Public Health. 2016 Aug 15; 16:787

A review of testing used in seroprevalence studies on measles and rubella

Dimech W, Mulders MN
VACCINE. 2016 Jul 29; 34 (35):4119-22

A 16-year review of seroprevalence studies on measles and rubella

Dimech W, Mulders MN
VACCINE. 2016 Jul 29; 34 (35):4110-8

Where to Now for Standardization of Anti-Rubella Virus IgG Testing

Dimech W
J Clin Microbiol. 2016 Jul; 54(7):1682-3

Standardization of Assays That Detect Anti-Rubella Virus IgG Antibodies

Dimech W, Grangeot-Keros L, Vauloup-Fellous C.
Clin Microbiol Rev
. 2016 Jan; 29(1):163-74

Seminal plasma anti-HIV antibodies trigger antibody-dependent cellular cytotoxicity: Implications for HIV transmission

Parsons MS, Madhavi V, Ana-Sosa-Batiz F, Center RJ, Wilson KM, Bunupuradah T, Ruxrungtham K, Kent SJ.
J Acquir Immune Defic Syndr
. 2016 Jan 1; 71(1):17-23

 

Summary of the Serology Screening Information Programme - 2015

M Karakaltsas
NRL

 

Where to Now for the Standardisation of Anti-rubella IgG Testing

Dimech W
NRL, Fitzroy, Victoria, Australia
J. Clin. Microbiol. doi:10.1128/JCM.00800-16

 

A 16-Year Review of Seroprevalance Studies on Measles and Rubella

Dimech W1, Mulders MN2
1 NRL, Fitzroy, Victoria, Australia

2 World Health Organization, Global VPD Laboratory Networks, 20, avenue Appia, CH-1211 Geneva 27, Switzerland
Vaccine 2016 Vol (16) 30401-7 (Epub ahead of print)

 

A Review of Testing Used in Seroprevalence Studies on Measles and Rubella

Dimech W1, Mulders MN2
1 NRL, Fitzroy, Victoria, Australia
2 World Health Organization, Global VPD Laboratory Networks, 20, avenue Appia, CH-1211 Geneva 27, Switzerland
Vaccine 2016 Vol (16) 30405-4  (Epub ahead of print)

 

Standardization of Assays That Detect Anti-Rubella Virus IgG Antibodies

Dimech Wa, Grangeot-Keros Lb, Vauloup-Fellous Cb
a NRL, Fitzroy, Victoria, Australia
b Paris-Sud University AP-HP, Hopital Paul Brousse, Virologie, National Reference Laboratory for Maternofetal Rubella Infections, Villejuif, France

Clin Microbiol Rev 2016 Vol 29 (1)163–174.

 

Summary of the Serology Screening Information Programme - 2014

Karakaltsas M
NRL


Visual and Statistical Assessment of Quality Control Results for the Detection of Hepatitis-B Surface Antigen among Australian Blood Donors

Wand H1, Dimech W2, Freame R3 and Smeh K2
1 The Kirby Institute, University of NSW, Sydney, NSW 2052, Australia.
2 NRL, 4th Floor, Healy Building, 41 Victoria Parade, Fitzroy, VIC 3065, Australia.
3 Australian Red Cross Blood Service, 44 Musk Ave. Kelvin Grove, Brisbane, QLD 4059, Australia.
Annals of Clinical and Laboratory Research, 2015 Vol. 3 No. 2:8

 

Increased testing for Neisseria gonorrhoeae with duplex nucleic acid amplification tests: implications for surveillance

Donovan B, Dimech W, Ali H, Guy R, Hellard M on behalf of the ACCESS Collaboration
1 Kirby Institute, Wallace Wurth Building, UNSW Australia, Sydney, NSW 2052, Australia.
2 Sydney Sexual Health Centre, Sydney Hospital, Sydney, NSW 2000, Australia.

3 National Serology Reference Laboratory, Fitzroy, Vic. 3065, Australia.
4 Burnet Institute, 85 Commercial Road, Melbourne, Vic. 3004, Australia.
Sex Health. 2015, 12, 48-50

Corresponding author: bdonovan@kirby.unsw.edu.au


Determination of quality control limits for serological infectious disease testing using historical data

Dimech W, Vincini G, Karakaltsas M
NRL, 4th Floor, Healy Building, 41 Victoria Parade, Fitzroy 3065 Victoria, Australia
Clin Chem Lab Med. 2014 Aug 12

 

Analysis of Laboratory Testing Results Collected in an Enhanced Chlamydia Surveillance System in Australia, 2008-2010

Dimech W, Lim MSC, Van Gemert C, Guy R, Boyle D, Donovan B and Hellard M
1 NRL, 4th Floor Healy Building, 41 Victoria Parade, Fitzroy 3065, Australia

2 Burnet Institute, Centre for Population Health, 85 Commercial Road, Melbourne, Victoria 3004, Australia

3 Monash University, School of Population Health and Preventive Medicine, 99 Commercial Rd, Melbourne 3004, Australia

4 The Kirby Institute, Sexual Health Program, University of New South Wales, Sydney, NSW 2052, Australia

5 GRHANITE Health Informatics Unit, Rural Health Academic Centre, Melbourne Medical School, University of Melbourne, 49 Graham Street, Shepparton, Victoria 3630, Australia

6 Sydney Sexual Health Centre, Sydney Hospital, Sydney, NSW 2000, Australia

BMC Infect Dis 2014 14, 325.

Corresponding author: Wayne Dimech wayne@nrl.gov.au

 

Multi-Centre Evaluation of the Determine HIV Combo Assay when Used for Point of Care Testing in a High Risk Clinic-Based Population

Damian P. Conway1*, Martin Holt2, Anna McNulty3,4, Deborah L. Couldwell5,6, Don E. Smith4,7, Stephen C. Davies8, Philip Cunningham9,10, Phillip Keen1, Rebecca Guy1 on behalf of the Sydney Rapid HIV Test Study
1 The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia,
2
Centre for Social Research in Health, University of New South Wales, Sydney,
New South Wales, Australia,
3
Sydney Sexual Health Centre, Sydney Hospital, Sydney, New South Wales, Australia,
4
School of Public Health and Community Medicine,
University of New South Wales, Sydney, New South Wales, Australia,
5 Western Sydney Sexual Health Centre, Western Sydney Local Health District, Sydney, New South Wales, Australia,
6
Sydney Emerging Infections and Biosecurity Institute, University of Sydney, Sydney, New South Wales, Australia,
7
Albion Centre, Surry Hills, Sydney, New South Wales, Australia,
8 North Shore Sexual Health Service, Royal North Shore Hospital, St Leonards, Sydney, New South Wales, Australia,
9 St Vincent’s Centre for Applied Medical Research, University of New South Wales, Sydney, New South Wales, Australia,
10
NSW State Reference Laboratory for HIV, St Vincent’s Hospital, Darlinghurst, Sydney, New South Wales, Australia

* E-mail: dconway@kirby.unsw.edu.au

PLOS ONE, 9(4):e94062, April 2014

 

Increasing access by priority populations to Australian sexual health clinics.

Ali H, Donovan B, Fairley CK, Chen MY, O'Connor CC, Grulich AE, McNulty A, Ryder N, Hellard ME, Guy RJ; ACCESS Collaboration
The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia; Sydney Sexual Health Centre, Sydney Hospital, Sydney, New South Wales, Australia;rMelbourne Sexual Health Centre, Melbourne, Victoria
Sex Transm Dis. 2013 Oct;40(10):819-21

 

External Quality Assessment For HIV Proviral-DNA Tropism Testing For An International Clinical Study-The Maraviroc Switch Collaborative Study (MARCH)

Land S1, Tu E2, Swenson L3, Kelleher A2,4, Kaye S5, Pett SL2, 4, Emery S2, Kaiser R6, Silk D2, Berthon-Jones N2, Harrigan PR3 for the MARCH Study Laboratory Group and MARCH study group
1NRL, Melbourne, Australia;
2The Kirby Institute, University of New South Wales, Sydney, NSW, Australia;
3BC Centre for Excellence in HIV/AIDS, Vancouver, British Colombia, Canada;
4Centre for Applied Medical Research (AMR), St Vincent’s Hospital, Sydney, NSW, Australia;
5Imperial College London, Norfolk Place, London, United Kingdom;
6Institut für Virologie, der Universität zu Köln, Cologne, Germany.

J Clin Microbiol. 2013 Jul;51(7):2063-71. doi: 10.1128/JCM.00510-13. Epub 2013 Apr 17.

 

A Review of the Relationship between Quality Control and Donor Sample Results Obtained from Serological Assays used for Screening Blood Donations for Anti-HIV and Hepatitis B Surface Antigen

Dimech W, Freame R, Smeh K and Wand H
NRL, Australian Red Cross Blood Service (QLD)

Accred Qual Assur 2013 Volume 18, Issue 1, pp 11-18

 

Capacity building and predictors of success for HIV-1 drug resistance testing in the Asia-Pacific region and Africa 

Land S, Zhou J, Cunningham P, Sohn AH, Singtoroj T, Katzenstein D, Mann M, Sayer D and Kantor R
NRL, Melbourne, Victoria, Australia
Journal of the International AIDS Society, 16:18580, July 2013

 

Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques

Xu Y, Weatherall C, Bailey M, Alcantara S, De Rose R, Estaquier J, Wilson K, Suzuki K, Corbeil J, Cooper D A, Kent S J, Kelleher D and Zaunders J
The Kirby Institute, The University of New south Wales, Sydney, New South Wales, Australia, Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia,
CNRS FRE3235, Universite Paris Descartes, Paris, France, Department of Molecular Medicine, Infectious Disease Research Center, CHUL Research Center and Laval University, Quebec, Quebec, Canada, NRL, Melbourne, Victoria, Australia, St. Vincent's Centre for Applied Medical Research, St. Vincent's Hospital, Sydney, New South Wales, Australia

Journal of Virology 87:(7):3760-3773, April 2013

 

Investigation into Low-Level Anti-Rubella Virus IgG Results Reported by Commercial Immunoassays

Dimech W, Arachchi N, Cai J and Wilson K
NRL, Melbourne, Victoria, Australia
Clinical and Vaccine Immunology 20:(2): 255-261, February 2013

 

Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to 'protective' human leukocyte antigen-B alleles in HIV controllers

French M A, Center R J, Wilson K M, Fleyfel I, Fernandez S, Schorcht A, Stratov I, Kramski M, Kent S J and Kelleher A D
School of Pathology and Laboratory Medicine, University of Western Australia, Department of Clinical Immunology, Royal Perth Hospital and PathWest Laboratory Medicine, Perth, Western Australia, Department of Microbiology and Immunology, University of Melbourne,
NRL, Melbourne, Victoria and Immunovirology Laboratory, St. Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia.
AIDS 2013, 27:(4):519-528

 

Summary of the Serology Screening Information Program - 2013

Karakaltsas M
NRL

 

Guidelines and recommendations for the quality-assured conduct of Point-of-Care testing for infectious diseases and drugs of abuse in Australia

Shephard M, Leibie A, Dimech W, Condi D and Nolan M
On behalf of the AIMS Working Committee on Point-of-Care Testing for infectious diseases and drugs of abuse
Aust J Med. Sci. 2012 Dec 33 (4) 143-156


Leptospirosis - importance of a One Health approach

Chappel R J and Smythe L D
NRL, Fitzroy, Victoria, Australia
WHO/FAO/OIE Collaborating Centre for Reference and Research on Leptospirosis, Health Services Support Agency, Queensland Health, Archerfield, Queensland, Australia

Microbiology Australia 33 (4): 21-23, November 2012

 

Nonoccupational post-exposure prophylaxis source tracing: is it really feasible in Australia?

Pierce AB, Armishaw J, Price B, Wright EJ, Dax EM, Fairley CK and Hoy JF
Victorian NPEP Service, Infectious Diseases Unit, The Alfred Hospital, Melbourne, Vic, Australia, Department of Medicine, Monash University, Melbourne, Vic, Australia, Centre for Virology, Burnet Institute, Melbourne, Vic, Australia, National Serology Reference Laboratory, Melbourne, Vic, Australia, Melbourne Sexual Health Centre, Melbourne, Vic, Australia and School of Population Health, University of Melbourne, Vic, Australia
HIV Medicine (2012) DOI: 10.111/j.1468-1293.2011.00986.x

 

High Rates of Undiagnosed HIV Infections in a Community Sample of Gay Men in Melbourne, Australia

Pedrana A E, Hellard M E, Wilson K, Guy R and Stoove M
Centre for Population Health, Burnet Institute, Melbourne, Victoria, Australia, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia, The Nossal Institute for Global Health, The University of Melbourne, Melbourne, Victoria, Australia, NRL, Melbourne, Australia, Faculty of Medicine, National Centre in HIV Epidemiology and Clinical Research, Sydney, New South Wales, Australia.
J Acquir. Immune. Defic. Syndr. (2012) 59(1): 94-98

 

Summary of the Serology Screening Information Program - 2012

Karakaltsas M
NRL

 

The Difference in Self-Reported and Biological Measured HIV Prevalence: Implications for HIV Prevention

Pedrana A E, Hellard M E, Guy R, Wilson K and Stoove M
Centre for Population Health, Burnet Institute, Melbourne, Victoria, Australia, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia, The Nossal Institute for Global Health, The University of Melbourne, Melbourne, Victoria, Australia, NRL, Melbourne, Australia, Faculty of Medicine, National Centre in HIV Epidemiology and Clinical Research, Sydney, New South Wales, Australia
AIDS and Behavior (2011) DOI 10.1007/s10461-011-0116-7

 

Assessment of the Heat Stability of Seven Rapid HIV Assays

Learmonth K M, Chiu Y-HC, Galang H, Nawang M J and Dax EM
NRL, St Vincent's Institute, Melbourne, Victoria, Australia, Research Institute for Tropical Medicine, Muntinlupa City,Philippines, WHO Western Pacific Regional Office, Manila, Philippines
Transactions of the Royal Society of Tropical Medicine and Hygiene Vol 105 (2011) 388-395

 

Photographed Rapid HIV Test Results Pilot Novel Quality Assessment and Training Schemes

Chiu Y-HC, Ong J, Walker S, Kumalawati J, Gartinah T, McPhee D and Dax EM
NRL, St Vincent's Institute, Melbourne, Victoria, Australia, Clinical Pathology Department, Medical Faculty, University of Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia, West Java Provincial Health Laboratory, West Java Health Office, Bandung, Indonesia, Dept. of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia
PLoS ONE (2011) 6(3): e18294

 

Immunoassays for the Diagnosis of HIV: Meeting Future Needs by Enhancing the Quality of Testing

Roderick J Chappel, Kim M Wilson, Elizabeth M Dax
National Serology Reference Laboratory Australia, Fitzroy, Victoria, Australia
Future Microbiology, October 2009, Vol. 4, No. 8, Pages 963-982

 

Transfusion Medicine and Safety

R Dodd, W Kurt Roth, P Ashford, EM Dax and G Vyas
American Red Cross Holland Laboratory, 15601 Crabbs Branch Way, Rockville, MD 20855, USA
Biologicals (2009) 37:62-70

 

An International Quality Control Programme for PRISM Chemiluminescent Immunoassays in Blood Service and Blood Product Laboratories

S. Walker, W. Dimech, P. Kiely, K. Smeh, B. Francis, M. Karakaltsas & E. M. Dax
National Serology Reference Laboratory Australia, Fitzroy, Victoria, Australia, Australian Red Cross Blood Service, South Melbourne, Victoria, Australia
Vox Sanguinis (2009) 97, 309-316

 

TREAT Asia Quality Assessment Scheme (TAQAS) to standardize the outcome of HIV genotypic resistance testing in a group of Asian laboratories

S Land, P Cunningham, J Zhou, K Frost, K Katzenstein, R Kantor, YM Chen, S Oka, A DeLong, D Sayer, J Smith, EM Dax and M Law
National Serology Reference Laboratory, Australia
J Virol Methods (2009) 159:185-93

 

Balancing reversion of cytotoxic T-lymphocyte and neutralizing antibody escape mutations within human immunodeficiency virus type 1 Env upon transmission

V Peut, S Campbell, A Gaeguta, RJ Center, K Wilson, S Alcantara, CS Fernandez, DF Purcell and SJ Kent
Department of Microbiology and Immunology, University of Melbourne, Melbourne, Australia
J Virol (2009) 83: 8986-92

 

Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm

MD Simek, W Rida, FH Priddy, P Pung, E Carrow, DS Laufer, JK Lehrman, M Boaz, T Tarragona-Fiol, G Miiro, J Birungi, A Pozniak, DA McPhee, O Manigart, E Karita, A Inwoley, W Jaoko, J Dehovitz, LG Bekker, P Pitisuttithum, R Paris, LM Walker, P Poignard, T Wrin, PE Fast, DR Burton and WC Koff
International AIDS Vaccine Initiative, New York, NY 10028, USA
J Virol (2009) 83:7337-48

 

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

LM Walker, SK Phogat, PY Chan-Hui, D Wagner, P Phung, JL Goss, T Wrin, MD Simek, S Fling, JL Mitcham, JK Lehrman, FH Priddy, OA Olsen, SM Frey, PW Hammond, G Miiro, J Serwanga, A Pozniak, DA McPhee, O Manigart, L Mwananyanda, E Karita, A Inwoley, W Jaoko, J Dehovitz, LG Bekker, P Pitisuttithum, R Paris, S Allen, S Kaminsky, T Zamb, M Moyle, WC Koff, P Poignard and DR Burton
Department of Immunology and Microbial Science and IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA
Science (2009) 326:285-9

 

Identification of Performance Problems in a Commercial Human Immunodeficiency VirusType 1 Enzyme Immunoassay by Multiuser External Quality Control Monitoring and Real-Time Data Analysis

J. Kim, C. Swantee, B. Lee, H. Gunning, A. Chow, F. Sidaway, C. Sherlock, R. Garceau, W. Dimech, L. Malloch, and CAHCLS Laboratories
National Laboratory for HIV Reference Services, Public Health Agency of Canada, Ottawa, and Ontario Agency of Health, Protection and Promotion, Etobicoke, Ontario, Alberta Provincial Health Laboratory, Edmonton and Calgary, Alberta,Saskatchewan Provincial Health Laboratory, Regina, Saskatchewan, St. Paul’s Hospital,Vancouver, British Columbia, and Georges Dumont Hospital, Moncton, New Brunswick, Canada; National HIV Serology Laboratory, Melbourne, Australia; and Canadian Association of HIV Clinical Laboratory Specialists
Journal of Clinical Microbiology, Oct. 2009, p. 3114–3120

 

Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques.

Kent SJ, De Rose R, Mokhonov VV, Mokhonova EI, Fernandez CS, Alcantara S, Rollman E, Mason RD, Loh L, Peut V, Reece JC, Wang XJ, Wilson KM, Suhrbier A, Khromykh A.
Department of Microbiology and Immunology, University of Melbourne, 3010, Australia.
Virology. 2008 May 10; 374 (2):528-34. Epub 2008 Feb 12.

 

Control of viremia and prevention of AIDS following immunotherapy of SIV-infected macaques with peptide-pulsed blood.

De Rose R, Fernandez CS, Smith MZ, Batten CJ, Alcântara S, Peut V, Rollman E, Loh L, Mason RD, Wilson K, Law MG, Handley AJ, Kent SJ.
Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.
PLoS Pathog. 2008 May 2;4 (5):e1000055.

 

Evaluation of Eight Anti-rubella Immunoglobulin G Immunoassays that Report Results in International Units per Milliliter.

Dimech W, Panagiotopoulos L, Francis B, Laven N, Marler J, Dickeson D, Panayotou T, Wilson K, Wootten R, Dax EM.
National Serology Reference Laboratory, Australia, St. Vincent's Institute, 4th Floor, Healy Building, 41 Victoria Parade, Fitzroy 3065, Department of Serology, Symbion Health, Dorevitch Pathology, 18 Banksia Street, Heidelberg 3084, Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead 2145, Microbiology Department, Southern Health, 246 Clayton Road, Clayton 3168, Department of Microbiology and Immunology, University of Melbourne, Parkville, 3052, Australia.
J Clin Microbiol. 2008 Apr 23

 

Assessing Interpretation Proficiency of Rapid HIV Assays in Non-Laboratory Settings: Ensuring the Quality of Testing.

Learmonth KM, McPhee DA, Jardine DK, Walker SK, Aye TT, Dax EM.
National Serology Reference Laboratory, Australia, St Vincent's Institute, Fitzroy, Victoria, Australia; Department of Medicine at St Vincent's Health, University of Melbourne, Fitzroy, Victoria, Australia; Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.
J Clin Microbiol. 2008 Mar 19 [Epub ahead of print].

 

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo.

Gorry PR, McPhee DA, Verity E, Dyer WB, Wesselingh SL, Learmont J, Sullivan JS, Roche M, Zaunders JJ, Gabuzda D, Crowe SM, Mills J, Lewin SR, Brew BJ, Cunningham AL, Churchill MJ.
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia.
Retrovirology. 2007 Sep 23; 4:66.

 

Viral Phenotypes and Antibody Responses in Long-Term Survivors Infected with Attenuated Human Immunodeficiency Virus Type 1 Containing Deletions in the nef and Long Terminal Repeat Regions

E E Verity, D Zotos, K Wilson, C Chatfield, V A Lawson, D E Dwyer, A Cunningham, J Learmont, W Dyer, J Sullivan, P R Gorry and D A McPhee
Department of Microbiology, Monash University, Clayton, Victoria, Australia, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, National Serology Reference Laboratory, Australia, St Vincent's Institute, Fitzroy, Victoria, Australia, School of Biological and Chemical Sciences, Deakin University, Burwood, Victoria, Australia, Centre for Virus Research, Westmead Millenium Institute, Westmead, New South Wales, Australia, Australian Red Cross Blood Service, Sydney, New South Wales, Australia, Dana-Farber Cancer Institute, Boston, Massachusetts and Department of Neurology, Havard Medical School, Boston, Massachusetts
Journal of Virology 81 (17) 9268-9278 Sep 2007

 

The Heterosexual HIV Type 1 Epidemic in Papua New Guinea is Dominated by Subtype C

C E Ryan, J Gare, S M Crowe, K Wilson, J C Reeder and R B Oelrichs
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, Department of Medicine, Monash University, Melbourne, Victoria, Australia, Papua New Guinea Institute for Medical Research, Goroka, PNG,
National Serology Reference Laboratory, Australia, Melbourne, Victoria, Australia, Global HIV/AIDS Program, The World Bank, Washington, D.C. USA, C.E.R. and J.G. contributed equally to this work.
AIDS Research and Human Retroviruses 23 (7) 941-944 Jul 2007

 

Phenotype and Envelope Gene Diversity of nef-deleted HIV-1 Isolated from Long-Term Survivors Infected from a Single Source

L Gray, M J Churchill, J Sterjovski, K Witlox, J C Learmont, J S Sullivan, S L Wesselingh, D Gabuzda, A L Cunningham, D A McPhee and P R Gorry
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia, Department of Medicine, Monash University, Melbourne, Victoria, Australia, Department of Pathology and Immunology, Monash University, Melbourne, Victoria, Australia, Australian Red Cross Blood Service, Sydney, New South Wales, Australia, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia, Dana-Farber Cancer Institute, Boston, MA, USA, Department of Neurology, Harvard Medical School, Boston, MA, USA, Westmead Millennium Institute, Westmead, New South Wales, Australia, National Serology Reference Laboratory, Australia and St. Vincent's Institute for Medical Research, Fitzroy, Victoria, Australia
Virology Journal 4 (75) Jul 2007

 

Macrophage Tropism and Cytopathicity of HIV-1 Variants Isolated Sequentially from a Long-Term Survivor Infected with nef-Deleted Virus

P R Gorry, D A McPhee, S L Wesselingh and M J Churchill
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, Department of Medicine, Monash University, Melbourne, Victoria, Australia, Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia, National Serology Reference Laboratory, Fitzroy, Victoria, Australia, St. Vincent's Institute, Fitzroy, Victoria, Australia
The Open Microbiology Journal 1 (7) 1-7 Jun 2007

 

The Prevalence and risk behavious associated with the transmission of blood-borne viruses among ethnic-Vietnamese injecting drug users

M E Hellard, O K Nguyen, R J Guy, D Jardine, A Mijch, P G Higgs
Centre for Epidemiology and Population Health Research, Macfarlane Burnet Institute for Medical Research and Public Health, Victoria, Department of Epidemiology and Preventive Medicine, Monash University, Victoria, National Serology Reference Laboratory, Australia, Victorian HIV/AIDS Service, Infectious Disease Unit, Alfred Hospital, Victoria
Australian and New Zealand Journal of Public Health 30 (6) 519-525 Nov 2006

 

HIV Testing in 2006: issues and methods

D Chang, EM Dax and K Learmonth
National Serology Reference Laboratory, Australia
Expert Review of Anti-infective Therapy 4 (4):565-582 Aug 2006

 

Comparative Evaluation of Simian, Simian-Human, and Human Immunodeficiency Virus Infections in the Pigtail Macaque (Macaca nemestrina) Model

C J Batten, R De Rose, K M Wilson, M B Agy, S chea, I Stratov, D C Montefiori and S J Kent
Department of Microbiology and Immunology, University of Melbourne, Victoria, Australia, National Serology Reference Laboratory, Australia, Fitzroy, Victoria, Australia, Washington Regional Primate Research Center, University of Washington, Seattle, Washington, USA and Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA
AIDS Research and Human Retroviruses 22 (6) 580-588 June 2006

 

Transcriptional activity of blood- and cerebrospinal fluid-derived nef/long-terminal repeat sequences isolated from a slow progressor infected with nef-deleted human immunodeficiency virus type 1 (HIV-1) who developed HIV-associated dementia

M J Churchill, A Figueiredo, D Cowley, L Gray, D F J Purcell, J S Sullivan, D A McPhee, S L Wesselingh, B J Brow and P R Gorry
Macfarland Burnet Institute of Medical Research and Public Health, Melbourne, Victoria, Australia, Departments of Microbiology and Medicine, Monash University, Melbourne, Victoria, Australia, Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia, Australian Red Cross Blood Service, Sydney, New South Wales, Australia, Faculty of Medicine, University of Sydney, New South Wales, Australia, National Serology Reference Laboratory, Australia, St. Vincent's Institute for Medical Research, Fitzroy, Victoria, Australia and Department of Neurology, St. Vincent's Hospital, Darlinghurst, New South Wales, Australia
Journal of NeuroVirology 12 219-228 May 2006

 

Point of care using simple/rapid HIV tests

K Learmonth, D McPhee and E M Dax
National Serology Reference Laboratory, Australia
Microbiology Australia 82-83 May 2006

 

Humoral Immune Response to Primary Rubella Infection

K M Wilson, C Di Camillo, L Doughty and E M Dax
National Serology Reference Laboratory, Australia
Clinical & Vaccine Immunology 13 (3):380-386 2006

 

Broad neutralisation and complement-mediated lysis of HIV-1 by PEHRG214, a novel caprine anti-HIV polyclonal antibody

E E Verity, L A Williams, D Haddad, V Choy, C O'Loughlin, C Chatfield, N Saksena, A Cunningham, F Gelder and D A McPhee
Department of Microbiology, Monash University, clayton, Victoria, Australia, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, Virionyx Corporation, Auckland, New Zealand, National Serology Reference Laboratory, Australia, Fitzroy, Victoria, Australia, National Centre in HIV Virology Research, Melbourne, Victoria, Australia, Retroviral Genetics Division, Westmead Millenium Institute, Sydney, New South Wales, Australia
AIDS 20 (4):505-515 2006

 

Calculating Uncertainty of measurement for Serology Assays by Use of Precision and Bias

W Dimech, B Francis, J Kox and G Roberts
National Serology Reference Laboratory, Australia, Fitzroy, Victoria, Australia; National Association of Testing Authorities, North Melbourne, Victoria, Australia;
Clinical Chemistry 52 (3) 526-529 Jan 2006

 

Use of Participant EQA Results to Assess Sample Homogeneity and Stability for Qualitative Analytes

D Tholen, R Chappel and B Francis
Dan Tholen Statistical Consulting Services, Michigan, USA and National Serology Reference Laboratory, Australia
Accred. Qual. Assur. 11 (8-9) 400-407 Aug 2006

 

Commercial Enzyme immunoassay Adapted for the Detection of Antibodies to Hepatitis C Virus in Dried Blood Spots

H A Croom, K M Richards, S J Best, B H Francis, E I M Johnson, E M Dax and K M Wilson
National Serology Reference Laboratory, Australia
Journal of Clinical Virology 36 68-71 2006

 

Advances in Transfusion Safety - Vol. 4

E M Dax, A Farrugia and G N Vyas
National Serology Reference Laboratory, Victoria, Australia, Therapeutic Good Administration, ACT, Australia, The Medical Center, University of California, San Francisco, California, USA
International Conference, Sydney, October 2005: Proceedings, Book 2007

 

Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3

S J Kent, C J Dale, C Ranasinghe, I Stratov, R De Rose, S Chea, D C Montefiori, S Thomson, I A Ramshaw, B E Coupar, D B Boyle, M Law, K M Wilson, A J Ramsay
Department of Microbiology and Immunology, University of Melbourne, Vic., Australia, National Serology Reference Laboratory, Fitzroy, Vic., Australia
Vaccine 23 (42):5009-21 2005

 

Evaluation of three immunoassays used for detection of anti-rubella virus immunoglobulin M antibodies

W Dimech, L Panagiotopoulos, J Marler, N Laven, S Leeson, E M Dax
National Serology Reference Laboratory, Australia, Fitzroy, Victoria, Australia, Department of Serology, Mayne Health, Dorevitch Pathology, Heidelberg, Victoria, Australia, Department of Serology, Mayne Health, Laverty Pathology, North Ryde, NSW, Australia
Clin Diagn Lab Immunol. 12 (9):1104-8 Sep 2005

 

Subtype AE HIV-1 DNA and recombinant Fowlpoxvirus vaccines encoding 5 shared HIV-1 genes: safety and T cell immunogenicity in macaques

R De Rose, S Chea, CJ Dale, J Reece, CS Fernandez, KM Wilson, S Thomson, IA Ramshaw, BEH Coupar, DB Boyle, MT Sullivan & SJ Kent
National Serology Reference Laboratory, Fitzroy, Vic., Australia; Department of Microbiology and Immunology, University of Melbourne, Royal Parade, Vic., Australia
Vaccine 23 (16):1949-1956 2005

 

A phase I study of the pharmacokinetics and safety of passive immunotherapy with caprine anti-HIV antibody, HRG214, in HIV-1 infected individuals

S L Pett, L A Williams, R O Day, A R Lloyd, A D Carr, K R Clezy, S Emery, E Kaplan, D A McPhee, A J McLachlan, F B Gelder, S R Lewin, W Liauw, K M Williams
HIV Clin Trials 5 (2):91-8 2004

 

Longitudinal Analysis of nef/LTR-deleted HIV-1 in Blood and CSF of a Long-Term Survivor who developed HIV-Associated Dementia

M Churchill, J Sterjovski, L Gray, D Cowley, C Chatfield, J Learmont, J S Sullivan, S M Crowe, B J Brew, S L Wesselingh D A McPhee and P R Gorry
National Serology Reference Laboratory, Australia, Macfarlane Burnet Institute for Medical Research and Public Health, Department of Medicine, Monash University, Melbourne, Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia, Australian Red Cross Blood Service, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia and St. Vincent's Hospital, Darlinghurst, NSW, Australia
Journal of Infectious Diseases 190 2181-6 Dec 2004

 

Apoptosis induced in synchronized human immunodeficiency virus type 1 infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein

V A Lawson, K A Silburn, P R Gorry, G Paukovic, D F J Purcell, A L Greenway, D A McPhee
Virology 327 70-82 2004

 

Advances in laboratory testing for HIV

E M Dax & A Arnott
National Serology Reference Laboratory, Fitzroy, Vic., Australia;
Pathology 36 (6):551-560 2004

 

Incidence Immunoassay for Distinguishing Recent from Established HIV-1 Infection in Therapy Naive Populations

KM Wilson, EIM Johnson, HA Croom, KM Richards, L Doughty, PH Cunningham, BE Kemp, BM Branson & EM Dax
National Serology Reference Laboratory, Fitzroy, Vic., Australia;
AIDS 18 (17):2253-2259 2004

 

Evaluation in macaques of HIV-1 DNA vaccines containing CpG motifs and fowlpoxvirus vaccines co-expressing IFNg or IL-12

CJ Dale, R De Rose, KM Wilson, HA Croom, S Thomson, BEH Coupar, A Ramsay, DFJ Purcell, R French, M Law, S Emery, DA Cooper, IA Ramshaw, DB Boyle & SJ Kent for the Australia; Australian Thai HIV Vaccine Consortium
National Serology Reference Laboratory, Fitzroy, Vic., Australia; Department of Microbiology and Immunology, University of Melbourne, Royal Parade, Vic., Australia
Vaccine 23 (2):188-197 2004

 

Impact of Proficiency Testing for the Microscopic Agglutination Test for Leptospirosis

RJ Chappel, M. Goris, MF Palmer and RA Hartskeerl
National Serology Reference Laboratory, Fitzroy, Vic., Australia; Leptospirosis Reference Centre (WHO/FAO/OIE), Royal Tropical Institute, Amsterdam, The Netherlands; Leptospira Reference Unit, County Hospital, Hereford , UK.
J. Clin. Microbiol. 42 (12):5484-5488 2004

 

Continuing education in clinical microbiology: a survey to determine scientists' attitude to existing programmes

W Dimech and D Grando
National Serology Reference Laboratory, Fitzroy, Vic., Australia; RMIT University, Melbourne, Australia
Australian Journal of Medical Science 25 (3):129-139 2004

 

Comprehensive quality control programme for serology and nucleic acid testing using an internet-based application

W Dimech, S Walker, D Jardine, S Read, K Smeh, M Karakaltsas, B Dent and EM Dax
National Serology Reference Laboratory, Fitzroy, Vic., Australia
Accred. Qual. Assur. 9 148-151 2004

 

Validation of assembled nucleic acid-based tests in diagnostic microbiology laboratories

W Dimech, DS Bowden, B Brestovac, K Byron, G James, D Jardine, T Sloots and EM Dax
National Serology Reference Laboratory, Fitzroy, Vic., Australia
Pathology 36 (1):45-50, 2004

 

External Quality Assessment Schemes and Their Value to Blood Services

EM Dax
National Serology Reference Laboratory, Australia
Indian J. Hemat & Blood Transf. Vol. XXI: Suppl 3 66-68 2003

 

New precision in measuring trachoma infection

HR Taylor, EM Dax
Centre for Eye Research Australia, University of Melbourne, East 3002, Melbourne, Australia
Lancet 362 (9379):181-182 2003

 

Calibration of HIV-1 working reagents for nucleic acid amplification techniques against the 1st international standard for HIV-1 RNA

C Davis, A Heath, S Best, I Hewlett, N Lelie, R Schuurman and H Holmes
Division of Retrovirology, National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, UK
J. Virological Methods 107 (1):37-44 2003

 

A Quality Assessment Program (QAP) for Genotypic Antiretroviral Testing (GART) Results in an improvement in the detection of drug resistance mutations

DC Sayer, S Land, L Gizzarelli, M French, G Hales, S Emery, EM Dax and FT Christiansen
Department of Clinical Immunology and Biochemical Genetics, Royal Perth Hospital, Perth 6000, Western Australia, Australia
J. Clin. Micro. 41 (1):227-236 2003

 

Anti-HCV conformity testing of voluntary blood donors: comparison of the sensitivity of two immunoblot assays

P Kiely, L Eliades, M Kebede, M Stephenson and D Jardine
Virus Serology Unit, Australian Red Cross Blood Service-Victoria, South Melbourne
Transfusion 42(8):1053-1058 2002

 

Sensitivity of HCV-RNA and HIV-RNA blood screening assays

PN Lelie, AAJ van Drimmelen, HTM Cuypers, SJ Best , SL Stramer, C Hyland, JP Allain, P Moncharmont, C Defer, M Nubling, A Glauser, M da Silva Cardoso, JF Viret, M Lankinen, L Grillner, U Wirthmuller, V Coste, B Masecar and EM Dax
VQC Laboratory, Sanquin-CLB Diagnostic Division, Amsterdam, The Netherlands.
Transfusion, 42(5):527-536 2002

 

Underestimation of HIV type 1 drug resistance mutations: results from the ENVA-2 genotyping proficiency program

R Schuurman, D Brambilla, T de Groot, D Huang, S Land, J Bremer, I Benders and CA Boucher
Department of Virology, University Medical Center Utrecht, The Netherlands
AIDS Research and Human Retrovirus Journal, Vol 18 (4) 243-248 2002

 

Variant Creutzfeldt-Jakob disease in Australian blood donors: estimation of risk and the impact of deferral strategies

P Correll, MG Law, C Seed, A Gust, M Buring, EM Dax, A Keller and JM Kaldor
National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia.
Vox Sang, Vol 81 6-11 2001

 

External Quality Assessment program for Chlamydia trachomatis Diagnostic testing by Nucleic Acid Amplification Assays

S Land, S Tabrizi, A Gust, E Johnson, S Garland and E.M Dax
National Serology Reference Laboratory, Australia & Royal Women’s Hospital
J. Clin. Micro. 40 (8). 2893-2896, August 2002

 

Specific Antibody Responses to an HIV-1 Vaccine

A.R.Sands, S.J.Kent, E.M.Dax and E.I.M. Johnson
National Serology Reference Laboratory, Australia, Department of Microbiology and Immunology, University of Melbourne, Parkville, Australia
(Proceedings of the 6th European Conference on Experimental AIDS Research, Edinburgh, UK, 23-26th June, 2001).

 

Anti-HIV Quality Assurance Programs in Australia and the Southeast Asian and Western Pacific Regions

Gust A, Walker S, Chappel R.J and Dax E.M
National Serology Reference Laboratory, Australia
Accred. Qual. Assur. 6 168-172

 

New Leptospires Infecting Australian Pigs

R.J.Chappel, S.D. Driesen, K.A. Moore, D.A. Khalik

 

Quality and Laboratory Diagnosis of HIV Infection

Christopher W. Hamilton & Elizabeth M. Dax
National Serology Reference Laboratory, Australia
Microbiol Australia, Vol 22 (1) 2001